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KMID : 0388220080150030273
Journal of the Korean Rheumatism Association
2008 Volume.15 No. 3 p.273 ~ p.276
A Case of Peripheral Neuropathy in a Patient with Rheumatoid Arthritis Treated with Leflunomide
Kim Hyun-Chul

Kim Seung-Hyun
Jun Jae-Bum
Kim Hee-Sun
Lee Kyeong-A
Kim Dam
Abstract
Leflunomide is a new disease-modifying drug licensed for treatment of rheumatoid arthritis. Recently, neuropathy has been reported with leflunomide. We report a case of peripheral neuropathy in rheumatoid arthritis treated with leflunomide. Nerve conduction study and electromyogram show sensory-motor polyneuropathy of both upper and lower limbs. Leflunomide medication was discontinued and cholestryamine washout was performed with some improvement in a couple of weeks.
KEYWORD
Leflunomide, Neuropathy, Arthritis Rheumatoid
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